SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b76b0a33a0de92996ad8581edde3b7dcb91ed6b33bd2e8dfe40cc5c9747c893' 
  AND token = 'ZtOcTkrz5c+UCtZiTJdjdcXMFctFGHK6/c8E4NhBRRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}