SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd7e9048470ed339225b425b7c82692100d925f5357cc573ae94c95236c03672' 
  AND token = 'p92D8i6HiOGBqKYCv1QSPMq8vofyed9y7RVfdEpN5eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}