SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2779cd2b7f1ff1e77225fa16146084316b6c3385994fabe236648a7a653ffb76' 
  AND token = 'oTV7D9tUQ2fSNwqCzr8xOSQYbrKC1skpQe8XcEEjHDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}