SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38fddd3a4a4a4954cf183b9a11a658e030ff7772346871a09d24b1ba4b469482' 
  AND token = 'aJPyWv2UEXNFMLo+bwPPacPeSCdKxWhKIEpYT854+qY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}