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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80f9061be2cb1e0307f7623a5d6fc8604b5018eceb7977f823afedd168a75050' 
  AND token = '/H68Xl53z3vUteE2A83uU10pI+N/DM5+noV4XXpFg3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}