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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dadbd06f7f62356fea989325cf950678cfd9b296c6ce76a6e08a5d380376283' 
  AND token = 'DunsC9EcJ4WtpGWgEfcLB+T4fPbk+vt+XAFSvTeLwpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}