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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '327a052a9464a251dde13c50b6ef2f8e40e3adbda939b23899833eb15c8f262f' 
  AND token = 'DumHsHlzL5S99ZW9I8ur9t7R0XqYoVXUtPXqUsyjoHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}