SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21ac61fa95bea3567be753a6e0609416a5b2d89ede76c6ed0489d84302ba1c4c' 
  AND token = 'Uxrx1vic96pam3NJVDPEj7RYCVBnfJLUvbZWVgEHs6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}