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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df077551127f4f3a913315c55482d8010ddfdb9c2e7d1be32f00ca143cdb6f3e' 
  AND token = 'iBeXXeRKixbjdXFStmELzcjQCR2ghuCxWZFn7qaoIrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}