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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48983a0b959f14749be78aeaa06f7e408b4700882976255977f11e287a403c7a' 
  AND token = 's1ZzEfsPHlk+rF1o/boHM3nzaWO/SnEIsgwQd+sSi9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}