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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d917df37ab0c88e4f82c644b1cdea9390fbbd4126916350e4d392840065fe81' 
  AND token = 'HW4WMy4tzJm9WzIkW2GtxdhO/JjeL9iLX/1smGaIuqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}