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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1cb33352aec52f4b7417f80533786a118d289cd4788a3694a3a26d160b759d6' 
  AND token = 'Q6aAltiIdJTCIGHRWQD6+qAP4Sf7S4j1XuSda+CgMGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}