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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '253885de907ec85b6de2a96fbd22328d73a07c4f31e40227e9d89cf1e2accefa' 
  AND token = '2PleuvrV6TiuDD3qyAF+uWTA6kSSh+nwHTpTjwV6O2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}