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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e86862188286b8d0ec5434785c300fda9fc0262ef41cf908c8505ec765dc7c95' 
  AND token = 'aKha9BkzXbTozivBbeo6S3C5uqg2nO6+HzVtCV6dnE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}