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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72bcb6b6e4611ea2b61d89c0eee0030b332032a26c498f362b6c2654d6836d41' 
  AND token = 'XtoqFqCcLMLqq5W1nLAq7fRSFZNFw0ceJ/3h+aM26y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}