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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b54e179501509b028fe440e2b86f8fd0e1b39b0f755b275e5b5f14ecc5c43777' 
  AND token = 'NL8eGxSsEjqGR/cIHgLw7RX2qGbeNdIbaqzDicbCeIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00083

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}