SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aab3d067e257ea63dbc056ceaa789f2a2581f6dbd5d9b660f4baecfb2e0a956a' 
  AND token = 'lN6+SJCrFsZWg7gQVSeYCRzPeSkTc0bJdFwriAxm8OQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}