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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '044fe9f842f05fa8240945449f467a8a03d7e080e61b2ef1d870ebfb8f9e428b' 
  AND token = 'fvkHCJBT4/xdZdVNcmplnbBZl2s+rdRyIiCv/zbFf1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}