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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ed8c501ceb91858e8bc9a61e8dfa1437cda16e58a683e54c4de7fb0be16d08a' 
  AND token = 'ZM+4wb48zstF2qVl6+br6tXKFyz/s/qDPCS+HUyHkOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}