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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5489547b83bd9df5780e5c84ab923c0552ef0a78d29f25382f11fc402db6c182' 
  AND token = 'tIveMS/Kthjg5fRe315zCVMZNAsozvl1XVt06pcZ6RU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}