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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4df1f105977564f9d0f4d8d0f150224d3c666cd348017d4f0c1636ef523b9696' 
  AND token = 'ZTlk4RnWS5yKFdFPiFzft2z0AvmJw0/4QveB2rDEgcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}