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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25ce1ce1125e9c08e00a853faa90d5a90daadb49353a066a3d1d5fbb182b4648' 
  AND token = '2tbCvOO3osCBewC3vP49Xj8SuMjFY6ZkAsFxq8oD6LA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}