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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44ddc7f30bc6e8fa477f438d3a057d008f14cac93bda7253b642c7ba5abf8be7' 
  AND token = '80LePc1S/X+zB21hlcM5RAB7PmpX3lBExJNdUbf4Of0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}