SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '487428de3ceab304a4f92b1dae87dc0801750ef5623a5258d922670191ef97d9' 
  AND token = '0PoCD7gX3bPFTeoIpkWr5UG/PU1ZVcxlzGAG8CFqBkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}