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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78da88b8cf9d2cbc80ca6e81a4a039594a6e3c88712db3f3b0ade4c09a7c0461' 
  AND token = '+4fwElO1r9KRls0FB4TbcuDnWwBxXf/cE54HT3LJ3jI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}