SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adc49f165ef398fd1d90b3fe697e3bcbb52d3d62c0ce0d3f6ad4130942709ad3' 
  AND token = 'yP8fhK23BXONMAbwzN976I3SyELIYXJsLpSp7fBZ2Uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}