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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a27b85c4ebb71bb9e40c447fafb8a6dd04d7ac8f52f301dc7a36e6d7dc81821' 
  AND token = 'cL5vjklOHzMf9MUFZhRGHeoix5is6GiOQBdV6DspGE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}