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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '344159064e5f43752ec5cb194a9abc74096e30bf81327523e370282a39f1cd2f' 
  AND token = 'YjVZbhLIgFvaCFBDZ4mZ6AW2XvfkovVvkfbkZLfLv/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}