SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4249233343feb3978087631392caf220e2f3ccbd3eaaf7789777ef374245e267' 
  AND token = 'ohnEe0+jx8n/vg8R4b96pFj2XMg4Wj3HQtrOS+YFDLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}