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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e536ba78f5235ff8e141c189d4ff13aa0185be577f45bde439aed0c478815338' 
  AND token = 'xO3X4flqvSRlGCMeB6x8TiJeLnagwCmq4FkeQYT1GM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}