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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b14645a3ca03d4805d61c1b9a8c2b58152a4d62328398fa7f599be3090204f0c' 
  AND token = 'OzUCq9fYWUKm7I2MjrqWRPPI9Y4FByeS07daAdE5S1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}