SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b8ea635c8a6c1a65ace17344b7edb1c5540237ef1bfa5a8de2012cba0c2c41b' 
  AND token = 'mMxPKlwT/bnVKYiT6YnuxAAA+3bTJyZgkM78flSBU/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}