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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cb4b9943d66c535d3a73fcbe08bef16c88a9c96f70be5b545265e0bb245e93d' 
  AND token = 'UXlVcKbn/CDTEbSOpyE9QmsRiy+ohtmG6F7kVwUk1PQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}