SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c525553efc1a4f04eee3c2a970177daa1cb764ef2be4cbf1bbb27873009907d8' 
  AND token = 'PcCm1JFk3V0AOYjLE3dIHUuvw8f8zQtTWLHs7TcOzsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}