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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e65f8b6b86470ddfda9cee8a20bd1df270f11f33a1036cef2805d4f41ff09ca' 
  AND token = 'k84bauZKbMXILCq1JM1JjnXptM0afJYP8UU/wyOhjIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}