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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5380b167fcbc3e9d0739bcc22f977ffca4486c4c235b224cd1f4a47fec3df97b' 
  AND token = 'SFc7PcMm0PkcM+MOSi9norh1klcYd0EzgdmIxNOvIHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}