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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb4573cabed12d1a37e35c360f8251c303499da422410536f83357d1d6b02cf1' 
  AND token = 'Kxd/8oJAVW9QoM9J0J3a68+TDOOgl56/F1iLohgcYT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}