SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '833fe3c7f59cb89e9a985aa3f5d838d939c23c04942daa68924331919c5fa70c' 
  AND token = 'xM0gnVQP8jHDaRi+k83SLuOwAnQQVXQMxfCVM5kca6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}