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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd48df7207d195614e0e91203d59952bb4cdec6a5a2a4a0ed52ed7f90797e9f53' 
  AND token = '8IVSaciKNck4ZgCAh/PZEMklYJQHxQEYZ1lMIcOASpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}