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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e6fd5a1e3217340b0e80df65f6be4a1185f2c44d3233633fab00285024dcb4b' 
  AND token = 'EvMg8iHXziX5VUUWLK7yva7fPyK7g6nTafZ6xGHm1oI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}