SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44bd83c9381de5200986733d6cfc4d38fff58bf0f32e4ad3966512b79bcdac09' 
  AND token = 'hoCpgiOXpcZKCleyZCf0MsoTTyBVrXMABr3ZD3eoVvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}