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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e6fa64e10502641f282099163e94ab10a13ff49285081121e680c9451f57537' 
  AND token = 'DuqJWZOsaYWeLGjXfeJ3jR2JibyxNQUtGjKDOAN0d7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}