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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b253a107047b14e2c07baa3ebd350c3abcbb0246b1ef2fb5698541f2c28606be' 
  AND token = '03iqu1RuSsh+XGF1BeRV/2vczXeEAQabQpMR3mVChz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}