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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0e9e709a47969e6de96cef1fba69e5a1a8a6667109233415b855d31a684aecc' 
  AND token = 'STMIaGiRzsUanFRuyO+2OMDLMp8+MgZxaLz9z5oNuew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}