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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef7ae2621de691f8af736beed2a6af19cbb016ac75a0c1c56885795d84b7f3b1' 
  AND token = '4EDNtHPbcyD2sXImifU/izgkeU/eFXPaAaVez7cPV94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}