SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9388a6351d1c029481a7eee071c392237c16360b25b8e2e07d3dc4b3b1ed87a2' 
  AND token = 'A7Wy6OeYzsv5r3GaRN81DzrW2PGeT1coktdvaBc3iNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}