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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac6a53dcda8c6648833ec3f66a56f52c59d2e8bbbbfbc4cb190e3e14fdd4fd58' 
  AND token = 'Dd24XmfYBXzVPD5FxU2gr93MQmQOnKvSDq1NDW16nhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}