SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e52267f96973d89c22a635214aaf884926fe82d646a4485c04cb4f4e802a40f' 
  AND token = 'hvTR0sj4kE5r/XprgkKuSCOKQcGU62C39ESe2C5jU2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}