SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54a2ca27fae4e1efb3a5ac063b4c5de7139b51e821e848596250fa01ec9a3850' 
  AND token = 'ICMJCkEQ19aPXWWFZ9CzehleW+gBZ4jqSza7daAbeYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}