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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64141dc4d7baa2dd8237a53c2686c0f5ad85caf3274c2eb24fd158864516a3f3' 
  AND token = '/oWd8K4MdQYgk1hWGlGxjvJuYxMF2fF1C4me81IpnFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}